卡前列素氨丁三醇与益母草注射液联合防治宫缩乏力性产后出血的临床观察

Prevention of postpartum hemorrhage by hemabate plus motherwort injection in high risk pregnant women

目的观察益母草注射液与卡前列素氨丁三醇联合防治宫缩乏力性产后出血的效果。方法选取221例有剖宫产指征且有高危因素者,随机分为安慰剂组、益母草组、卡前列素氨丁三醇组和卡前列素氨丁三醇+益母草组,观察第三产程时间、产后2h及24h出血量并进行比较。结果卡前列素氨丁三醇+益母草组的第三产程的时间比其他组的第三产程时间短,卡前列素氨丁三醇+益母草组的2h和24h产后出血量比其他组的出血量要少。结论益母草注射液联合卡前列素氨丁三醇应用对预防和减少产后出血有良好的作用。

Objective To investigate the effect of hemabate plus motherwort injection in postpartum hemorrhage caused by uterine atony. Methods A total of 221 women were randomly divided into 4 groups., a placebo group, a mother wort injection group, a hemabate group, and a motherwort injection ＋ hemabate group. After the fetus delivery, the placebo group was given 5 mL saline; the motherwort injection group was given 20 mg motherwort injectiom the hemmbate group was given 250/lg hemmbate; while the motherwort injection ＋ hemabate group was given 20 rag motherwort injection and 250 btg hemmbate in the uterine muscle. The amount of bleeding within 2 and 24 h after the delivery, and the length of the third stage labor were compared among the 4 groups. Results The amount of bleeding within 2 and 24 h after the delivery in the motherwort injection ＋ hemabate group was significantly less than that in other groups （P〈0. 05）. The length of the third stage labor in the motherwort injection ＋ hemabate group was shorter than that in other groups （P〈0.05）. Conclusion Hemabate plus motherwort injection is more effective and safer in the reduction and prevention of atonic postpartum hemorrhage.