某院骨科2006～2010年鲍曼不动杆菌耐药及治疗情况分析

Drug resistance and therapy of Acinetobacter baumannii from 2006 to 2010 in an orthopaedic ward

目的了解某院骨科2006～2010年鲍曼不动杆菌耐药及治疗情况,为临床合理使用抗菌药物提供依据。方法对某院骨科2006年1月～2010年12月鲍曼不动杆菌耐药及治疗情况进行回顾性分析。结果鲍曼不动杆菌的分离率自2006年逐年上升,2010年显著高于2006年。2010年,鲍曼不动杆菌除对米诺环素和头孢哌酮-舒巴坦耐药率较低外,对其他抗菌药物的耐药率均较高。临床治疗上存在抗菌药物滥用现象。结论鲍曼不动杆菌的分离率和耐药率逐年上升,应加强其耐药性监测,合理使用抗菌药物。

Objective To investigate the drug resistance and therapy of Acinetobacter baurnannii （Ab） from 2006 to 2010 in an orthopaedic ward. Methods A retrospective analysis was used for the drug resistance and therapy of Ab from 2006 to 2010. Results The isolation proportion of Ab strains was increasing year by year, which was significantly higher in 2010 than in 2006. The resistance rates of Ab were high to most antibiotics except ceioperazone-sulbactam and minocycline. There was antibiotic abuse in clinical practice. Conclusion The isolation proportion and resistant rate of Ab strains are increasing. We should monitor the drug resistance and use antibiotics more rationally.