突发性聋高压氧治疗方案与疗程的选择

Application of hyperbaric oxygen therapy for sudden deafness

目的探讨高压氧治疗突发性聋(SD)采用不同方案与疗程对其疗效的影响,以提高治疗有效率。方法将80例SD患者分成两组进行药物联合高压氧治疗,每组40例,A组在每天上午药物治疗结束后再接受高压氧治疗,B组每天上午接受高压氧治疗后再行药物治疗。药物治疗持续2～3周,高压氧治疗持续1～3个疗程,每10天一个疗程。结果 A组总有效率77.5%(31/40),B组总有效率55%(22/40),两组总有效率比较存在差异(χ2=4.528,P=0.033)。无论是A组还是B组,高压氧第一个疗程后与第二、三个疗程后及第二与三个疗程后总有效率比较,差异均无统计学意义。结论药物联合高压氧治疗突发性聋时,在早晨使用药物后再行高压氧治疗疗效更佳。高压氧治疗一个疗程即可,更长的疗程对突发性聋的治疗意义不大。

Objective In order to increase the curative effect,the effects of different hyperbaric oxygen therapy plans and the courses of treatment for sudden deafness were explored.Methods 80 cases of sudden deafness were divided into two groups（each group with 40 cases）.Hyperbaric oxygen treatment was given every morning before（group A） or after the drug treatment（group B）.Drug treatment lasted for 2-3 weeks,while The hyperbaric oxygen treatment was repeated for 1-3 courses.Each course of the treatment was 10 days.Results Total effective rates were significantly different between group A（77.5%,31/40） and B（55.00%,22/40）（χ2=4.528,P=0.033）.There was no difference between the first course of hyperbaric oxygen treatment and the second or third course.Conclusions For the patients with sudden deafness,it is better to apply hyperbaric oxygen treatment after the drug treatment rather than before.Because the first course of hyperbaric oxygen treatment has shown good curative effect,it is unnecessary to increase the courses.