长链脂肪酸对重症急性胰腺炎病人脂质介质的影响

The Effects of LCT Fat Emulsion on Lipid Mediators in Severe Acute Pancreatitis Patients.

观察长链脂肪酸对重症急性胰腺炎病人脂质介质的影响。方法：选择１２例重症急性胰腺炎病人，年龄６２．３岁±１５．０岁，随机分入脂肪乳剂组（７例）和非脂肪乳剂组（５例），脂肪乳剂组接受２０％脂肪乳剂输注２５０ｍｌ／ｄ，测定入院时、第２天、第４天测血前列腺素（ＴＸＢ_２、６－ｋｅｔｏ－ＰＧＦ_(１ａ)、ＰＧＥ_２）。结果：经４天治疗后两组血糖均获得较好控制，无高脂血症，而外周血前列腺素测定示，各组间和各时段间比较无差异。结论：静脉输注脂肪乳剂对血前列腺素无不良影响。

To investigate the effects of LCT fat emulsion on lipid mediators in severe acute pancreatitis(SAP). Methods: Tweleve SAP patients, 62.3±15.0 (yrs), were randomly allocated to fat group and non-fat group. Patients in fat group received 20% LCT fat emulsion 250ml per day. Blood glucose, triglyceride and prostaglandins (TXB_2.6-keto-PGF_(1a), PGE_2) in serum were determined at admitting day, second day and forth day. Results: Blood glucose and triglyceride in serum decreased after 4 days' therapy, and prostaglandin level showed no difference between the two groups. Conclusion: Fat emulsion had no adverse effects on prostaglandin in serum.