摘要
30例瓣膜置换术病人随机分为对照组 (Ⅰ组 )、异丙酚组 (Ⅱ组 )和咪唑安定组 (Ⅲ组 ) ,观察体外循环(CPB)期颈静脉血氧饱和度 (SjO2 )、动脉、颈内静脉血氧含量差 (Da vO2 )、脑氧摄取率 (CEO2 )的变化。结果表明 :复温时Ⅱ ,Ⅲ组SjO2 显著高于Ⅰ组 ,Da vO2 及CEO2 显著低于Ⅰ组 (P <0 .0 1,P <0 .0 5 ) ,且复温时SjO2 与CPB前相比差异无显著性。提示异丙酚与咪唑安定均能防止CPB时脑氧供需失衡。
Thirty patients undergoing heart valve replacement were divided randomly into three groups(n=10): control group, propofol group and midazolam group. Jugular bulb blood oxygen saturation(SjO 2),arterialvenous oxygen content difference(Da vO 2) and cerebral oxygen extraction rate(CEO 2) were measured at various periods of cardiopulmonary bypass(CPB). The results showed: SjO 2 decreased significantly, Da vO 2 and CEO 2 increased markedly during rewarming period in control group; but in propofol group and midazolam group, SjO 2, CEO 2 and Da vO 2 did not decline significantly compared with baseline. It is suggested that administering propofol or midazolam is helpful in avoiding cerebral oxygen supply and demand imbalance during CPB. [
出处
《湖南医科大学学报》
CSCD
2000年第1期65-67,共3页
Bulletin of Hunan Medical University
关键词
体外循环
异丙酚
咪唑安定
脑
供氧
cardiopulmonary bypass
propofol *
midazolan *
brain
jugular veins
