青年与老年胃癌的临床特点对比研究

Contrastive research on clinicopathologic characteristics of gastric cancer in young group and old group

目的 总结分析青年组与老年组胃癌的临床病理学特征 ,探讨其治疗方法。方法 对我院 1975～ 1993年底收治的 2 15 0例胃癌病人进行回顾性分析 ,并以直接法计算其生存率 ,用统计学方法进行对比分析。结果 青年组与老年组发病性别差异具有显著性 (P <0 0 5 ) ,青年组女性多发 ,老年组男性多发 ;胃癌部位 ,青年组以胃窦部居多 ,老年组虽然以胃窦部为主 ,但胃体底部比例增高 ;青年组病理组织类型分化差 ,老年组好于青年组 ,分化好 ;青年组淋巴转移血行转移均高于老年组 ,其差异有显著意义 ;老年组胃癌治愈性切除率高于青年组胃癌。青年组与老年组预后均较差。结论 青年组与老年组的临床病理学特征决定整体病期均较晚 ,故预后差。因此 ,提高两组的治愈率 ,早期发现 ,早期诊断 。

Objective To analyse the clinical pathological characteristics of gastric cancer in young group and old group and inquire into the methods of treatment.Methods We analysed 2 150 cases of gastric cancer which were treated in our hospital from 1975 to 1993 and calculated its subsistence rate using direct method,then analysed contrast with method of statistics.Results The sexual difference of young group and old group was highly remarkable ( P <0.05),the incidence of cancer of female was higher in young group that of male was higher old group;the location of cancer were mainly gastric antrum in young group and old group,but the incidences of cancer body of stomach was increasing in old group the differentiation for histo pathological ws better in old group than that in young group;the rate of lymph metastasis and blood metastasis in young were higher than that in old group;the resection rate of curing of gastric cancer in old group was higher than that in young group.The prognoses of young group and old group were worse.Conclusion The clinical pathological characteristics of gastric cancer in young group and old group make the whole disease period later,so the prognoses are worse.Thus,it is the key that to improve the curing rate of two groups and discover early,diagnose early,decrease the cases of advanced stage.