摘要
目的探讨胶质瘤术后放射性脑病与胶质瘤复发的鉴别。方法回顾分析我院2005年4月~2010年8月6例胶质瘤术后经放射治疗误诊为胶质瘤复发的临床资料。结果 5例病变全切,1例大部切除(切除90%)。6例病理结果为放射性脑病。1例术后右侧肢体肌力较术前转差(术前Ⅳ级,术后Ⅰ~Ⅱ级)。术后9~14 d出院。6例随访6~24个月,平均9.5月,患者恢复良好1,例术后8个月因胶质瘤复发再次入院。结论胶质瘤术后放射性脑病与胶质瘤复发难以区别,临床上容易误诊,应综合患者病史、复发时间、临床症状、影像学表现等多因素特征,提高临床鉴别诊断水平,降低误诊率的发生。
Objective To investigate the differentiation diagnosis between recurrent glioma and postoperative radiation encephalopathy. Methods We reviewed retrospectively the clinical data of 6 cases of glioma which were misdiagnosed as recurrent tumor after surgical treatment and radiotherapy in our hospital between April 2005 and August 2010. Results In the 6 cases, total excision was performed on 5 cases, and partial removal (90%) in the other one. Pathological examination showed radiation encephalopathy in all the 6 cases. One of the patients showed lower strength of the left limb (decreased from grade 1V preoperation to grade Ⅰ- Ⅱ postoperation). The patients were discharged from the hospital in 9 to 14 days, and 6 of them were followed up for a mean of 9.5 months (6 - 24 months). All the patients recovered well, except for one, who was admitted to hospital again in 8 months because of recurrent glioma. Conclusions It is difficult to differentiate radiation enccphalopathy from recurrent glioma. Medical history, recurrent time, symptoms, imaging results may contribute to diagnosis.
出处
《中国微创外科杂志》
CSCD
2012年第2期136-139,共4页
Chinese Journal of Minimally Invasive Surgery
关键词
放射性脑病
胶质瘤复发
误诊
Radiation eneephalopathy
Recurrent glioma
Misdiagnosis