轮状病毒感染性腹泻合并多器官功能损害40例临床分析

Clinical analysis of 40 infants with rotavirus infectious diarrhea complicated by multiple organ function damage

目的探讨轮状病毒感染性腹泻合并多器官功能损害的临床表现及诊疗方法。方法选取2010-12～2011-03我院儿科住院的轮状病毒感染性腹泻合并多器官功能损害患儿40例。入院后均采集新鲜大便做轮状病毒抗原检测,并做大便培养,同时检测肝肾功能、心肌酶谱、血电解质、C反应蛋白。结果 40例患儿出现不同程度的呼吸系统症状、肝功能异常、尿常规检查异常、心肌酶异常、电解质和C反应蛋白改变等。结论出现轮状病毒感染性腹泻患儿易并发肠道外脏器功能损害,及时检测并给予早期治疗是防治的关键。

Objective To investigate the clinical diagnosis and treatment methods for rotavirus infectious diarrhea comblined with multiple organ function damage. Methods Forty infants with rotavirus infectious diarrhea complicated by multiple organ function damage treated in paediatric ward of our hospital from December 2010 to March 2011 were selected. After admission, fresh stool sample were collected for detecting rotavirus antigen, and stool cul- ture was performed, and the function of liver and kidney, myocardial enzyme, blood electrolyte and C-reactive protein were detected. Results There were respiratory symptoms at different degree, abnormal changes in urine routine, my- ocardial enzyme, electrolyte and CRP in 40 infants with rotavirus infectious diarrhea. Conclusion The infants with rotavirus infectious diarrhea are easily complicated by extraintestinal organ function damage, detecting timely and early treating are the key of prevention and treatment.