摘要
目的:研究中药姝乐颗粒制的制备工艺及定性鉴别。方法:利用正交实验设计优化提取条件,以收膏率为指标,采用二因素(煎煮时间和加水量倍数),三水平进行煎煮条件的选择。并采用薄层色谱法对制剂中川芎,当归,延胡索进行了定性鉴别。结果:优选出的煎煮条件为A1B1,即第一次加15倍量水煎煮15h,第二次加10倍量水煎煮10h。且薄层色谱斑点清晰。结论:本提取工艺及质量可行。
OBJECTIVE:To study the preparation technique and qualitative identification of ShuLe granules(preparation of chinese medicine).METHODS:The optimal extractive factors were found with orthogonal experiment design with table L 9(3 4),the index were the extraction recovery rate.Thin-layer chromatography was employed for qualitative identification of the herbs of Ligusticum Chuanxiog Hort, Angelica Sinensis (Oliv)and Corydalis Turtschaninovii Bess.RESULTS:The optimal extract technique was boiling two times,the first boiling 1.5h,adding 15 times content water,the second boiling 1.0h,adding 10 times content water,and definition of the sports was good.CONCLUSION:The extraction technique and the quality standards are feasible.
出处
《药学实践杂志》
CAS
2000年第1期21-24,共4页
Journal of Pharmaceutical Practice
关键词
姝乐颗粒剂
正交设计
薄层层析法
中药
ShuLe granules
orthogonal experimental design
qualitative analysis
TLC