复方磺胺甲噁唑片释放度的考察

Inspection on release test of compound sulfamethoxazole tablet

目的:考察复方磺胺甲唑片释放度。方法:参照美国药典(ⅩⅫ),采用桨法和双波长分光光度法测定5种不同厂家批次的复方磺胺甲唑片释放度。结果:5种不同厂家批次的复方磺胺甲唑片释放度有非常显著差异(P<001)。结论:有必要增加释放度检查以保证国产复方磺胺甲:目的:考察复方磺胺甲唑片释放度。方法:参照美国药典(ⅩⅫ),采用桨法和双波长分光光度法测定5种不同厂家批次的复方磺胺甲唑片释放度。结果:5种不同厂家批次的复方磺胺甲唑片释放度有非常显著差异(P<001)。结论:有必要增加释放度检查以保证国产复方磺胺甲唑质量。

OBJECTIVE:To determine the release rate of compound sulfanethoxazole tablet.METHODS:Refering to USP(ⅩⅫ), the release rate of the sample from five domestic plants was determined by dualwavelength spectrophotometry.RESULTS:The release rates of the sample from five domestic plants were markedly different( P<0 01 ).CONCLUTION:It′s necessary to determine the release rate for ensuring the quality of compound sulfamethoxazole tablet made in our country.