摘要
目的探索有效的胰头癌及壶腹周围癌的诊断方法。方法回顾性分析2009年1月至2011年6月收治的84例胰头癌及壶腹周围癌的临床资料。结果胰头癌组癌抗原(CA)19—9表达水平高于其它组,与壶腹癌组比较,差异有统计学意义(P〈0.05);十二指肠癌组的癌胚抗原(CEA)、CA125表达水平较高,与胰头癌组比较,差异有统计学意义(P〈0.05)。彩色超声、CT、MRI这3项影像学检查中,CT的诊断符合率高于彩色超声,且差异有统计学意义(P〈0.05)。CA19—9联合彩色超声对胰头癌及壶腹周围癌诊断的检出率为81.0%(68/84),较单独检测CA19—9和单独彩色超声检查检出率均有明显提高;CA19-9联合CT检查对胰头癌及壶腹周围癌联合诊断的检出率为92.9%(78/84),较单独CA19—9和CT检查检出率有明显提高。结论早期胰头癌及壶腹周围癌诊断困难,而联合应用不同检查方法可以提高正确诊断率。
Objective To explore the effective method in diagnosis of periampullary cancer and pancreatic head carcinoma. Methods A retrospective study was accomplished on the 84 cases of peri- ampullary cancer or pancreatic head carcinoma hospitalized from January 2009 to June 2011. Results CAI 9-9 expression in pancreatic cancer patients was higher than other groups, compared with the amp- ullary cancer group, the difference was significant (P 〈 0. 1)5 ) ; CEA, CA125 expression in duodenal cancer patients were higher than other groups, compared with the pancreatic cancer group, the differ- ence was significant (P〈0. 05);Among examinations of color Doppler ultrasound,CT and MRI, the difference of diagnosis rat between ultrasound and CT was statistically significant (x2 = 10. 286,P〈 0. 05). The diagnostic accuracy for periampullary cancer and pancreatic head carcinoma was 81. 0%(68/84), when CA19-9 combined with ultrasound,compared with CA19-9 detection rate 61.9 % (52/ B4) and ultrasound detection rate of 64 % (54/84); The diagnostic accuracy for periampullary cancer and pancreatic head carcinoma was 92. 9 % (78/84), when CA19-9 combined with CT, compared with CA19-9 detection rate 61.9 % (52/84) and CT detection rate 86 % (72/84). Conclusion Early diagnosis for periampullary cancer and pancreatic head carcinoma is difficult, but combined application of different inspection method can improve the diagnostic accuracy.
出处
《腹部外科》
2012年第1期40-42,共3页
Journal of Abdominal Surgery
关键词
肝胰管壶腹
胰腺肿瘤
诊断
Ampulla of vater
Pancreatic neoplasms
Diagnosis