糯米藤中黄酮类化学成分研究

Study on flavonoid chemical constituents contained in Memorialis hirta

目的:对糯米藤的化学成分进行研究。方法:运用多种色谱方法进行分离纯化,根据理化性质和波谱数据鉴定化合物的结构。结果:从糯米藤95%乙醇提取物的乙酸乙酯萃取部分中分离得到12个化合物,分别签定为异鼠李素(1),山柰酚(2),槲皮素(3),异鼠李素-3-O-α-L-鼠李糖苷(4),山柰酚-3-O-α-L-鼠李糖苷(5),异鼠李素-3-O-β-D-葡萄糖苷(6),山柰酚-3-O-β-D-葡萄糖苷(7),槲皮素-3-O-α-L-鼠李糖苷(8),槲皮素-3-O-β-D-葡萄糖苷(9),异鼠李素-3-O-芸香糖苷(10),山柰酚-3-O-芸香糖苷(11)和槲皮素-3-O-芸香糖苷(12)。结论:所有化合物均为首次从该属植物中分离得到。

Objective:To study the chemical constituents of Memorialis hirta.Method:Compounds were isolated and purified by multiple methods,and their structures were identified based on physicochemical property and spectrum data.Result:12 compounds were isolated from ethyl acetate from 95% ethanol extracts of M.hirta,they were isorhamnetin(1),kaempferol(2),quercetin(3),isorhamnetin-3-O-α-L-rhamnopyranoside(4),kaempferol-3-O-α-L-rhamnopyranoside(5),isorhamnetin-3-O-β-D-glucopyranoside(6),kaempferol-3-O-β-D-glucopyranoside(7),quercetin-3-O-α-L-rhamnopyranoside(8),quercetin-3-O-β-D-glucopyranoside(9),isorhamnetin-3-O-rutinoside(10),kaempferol-3-O-rutinoside(11) and quercetin-3-O-rutinoside(12),respectively.Conclusion:All compounds were obtained from the genus Memorialis for the first time.