流行性感冒疫苗的预防效果观察

Assessment of Preventive Effect of Influenza Vaccine

为了解流行性感冒(流感)疫苗的预防效果和安全性,于1996～1998年为健康军人及其家属共2378人接种流感疫苗(免疫组),并按儿童、成人、老年3个年龄段选取2280人设立对照组。经6个月追踪观察结果显示,流感疫苗对流感样症状的预防有效率在儿童、成人、老年组中为827%、696%和786%,平均774%,对预防上呼吸道感染症状的有效率分别是446%、507%和467%,平均478%。在第2年的观察中,接种流感疫苗的副反应率为12%。证实流感疫苗具有良好预防效果和安全性。

In order to investigate the preventive effect and the safety of influenza vaccine in Chinese population, 2378 healthy military people and their family members were vaccinated (vaccinated group) from the year 1996 to 1998, 2280 people without vaccination (control group) were included in 3 subgroups(children, adults, elders) according to their ages. During 6 months follow up after their vaccination, the final results demonstrated that the rates of prevention of vaccine against influenza like symptoms in children, adults and elders were 82.7%, 69.6% and 78.6% respectively, the average was 77.4%, and rates against upper respiratory infection symptoms reached 44.6%, 50.7% and 46 7% respectively, averagely 47.8%. During the 2nd year observation, the incidence of side effect was only 1.2%. The results demonstrate the good preventive effect and the safety of influenza vaccine.