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内皮型一氧化氮合成酶与蛛网膜下腔出血后脑血管痉挛关系的研究进展 被引量：1

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摘要 蛛网膜下腔出血（subarachnoid hemorrhage，SAH）是由于多种原因造成血液进人颅内或椎管内蛛网膜下腔所引起的综合征。脑血管痉挛（cerebralvasospasm，cvs）是蛛网膜下腔出血后最严重的并发症之一，具有较高的致死率和致残率^[1-3]，至今尚无特效药物预防或治疗。明确其发病机制.
作者 骆杨 徐善水
机构地区 皖南医学院弋矶山医院神经外科
出处 《中国临床神经外科杂志》 2012年第2期126-128,共3页 Chinese Journal of Clinical Neurosurgery
关键词 内皮型一氧化氮合成酶 蛛网膜下腔出血 脑血管痉挛
分类号 R743-35 [医药卫生—神经病学与精神病学] Q789 [生物学—分子生物学]
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参考文献17

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同被引文献15

  • 1胡厚源,颜伟,周林.肝X受体激动剂对高脂载脂蛋白E基因缺陷小鼠动脉壁一氧化氮合酶、增殖细胞核抗原和纤溶酶原激活物抑制剂1表达的影响[J].中国动脉硬化杂志,2006,14(6):511-513. 被引量：2
  • 2Martinez-Gonzalez N A, Sudlow C L. Effects of apolipoprotein E geno- type on outcome "after ischaemic stroke, intracerebral haemorrhage and subarachnoid haemorrhage[ J ]. J Neurol Neurosurg Psychiatry, 2006, 77(12) : 1329 - 1335.
  • 3Lanterna L A, Ruigrok Y, Alexander S, et al. Meta-analysis of APOE genotype and subarachnoid hemorrhage: clinical outcome and delayed ischemia[J]. Neurology, 2007, 69(8) : 766 -775.
  • 4Jung C S, luliano B A, Harvey-White J, et al. Assoeiation between cerebrospinal fluid levels of asymmetric dimethyl-L-arginine, an end.g- enous inhibitor of endothelial nitric oxide synthase, and eerebral vaso- spasm in a primate model of subarachnoid hemorrhage [ J ]. J Neum- surg, 2004, 101(5) : 836 -842.
  • 5Khurana V G, Smith L A, Baker T A, et al. Protective vasomotor eff- ects of in vivo recombinant endothelial nitric oxide synthase gene ex- pression in a canine model of cerebral vasospasm [ J ]. Stroke, 2002, 33 ( 3 ) : 782 - 789.
  • 6Huang Y, Weisgraber K H, Mucke L, et al. Apolipoprotein E: diver- sity of cellular origins, structural and biophysical properties, and effects in Alzheimer' s disease [ J ]. J Mol Neurosci, 2004, 23 ( 3 ) : 189 - 204.
  • 7Lin B, Dan W, Jiang L, et al. Association of APOE polymorphism with the change of the brain function in the early stage of aneurysmal subarachnoid hemorrhage [ J ]. Acta Neurochir Suppl, 2011, 110 ( Pt 1 ) : 39 -42.
  • 8Tang J, Zhao J, Zhao Y, et al. Apolipoprotein E epsilon4 and the risk of unfavorable outcome after aneurysmal subarachnoid hemorrhage [J]. Surg Neural, 2003, 60(5) : 391 -396.
  • 9Gallek M J, Conley Y P, Sherwood P R, et al. APOE genotype and functional outcome following aneurysmal subarachnoid hemorrhage [J]. Biol Res Nurs, 2009, 10(3) : 205 -212.
  • 10Wu H T, Zhang X D, Su H, et al. Association of apolipoprotein E polymorphisms with cerebral vasospasm after spontaneous subarach- noid hemorrhage [ J]. Acta Neurochir Suppl, 2011, 110 ( Pt 1 ) :141 - 144.

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中国临床神经外科杂志
2012年 第2期

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