鞍内非垂体腺瘤性病变

Non-pituitary Adenomatous Lesion in Sella Turcica

目的 :总结鞍内非垂体腺瘤性病变的临床特点及相关的发病因素。方法 :13例鞍内非垂体腺瘤性病变患者 ,男性5例 ,女性8例 ;年龄33～36岁。其中Rathke′s囊肿9例 ,垂体腺炎2例 ,原发性垂体脓肿1例 ,原发性垂体乳头状瘤1例 ,均采用鼻 -蝶入路手术摘除。结果 :术后全部患者临床均有不同程度改善和消失 ,无手术合并症 ,随访4个月～3年半无1例复发或死亡。结论 :鞍内非垂体腺瘤性病变 ,易误诊为垂体腺瘤 ,仔细询问病史至关重要 ,头颅MRI检查 ,有助于临床鉴别诊断。

Objective: To study the clinical features and related etiologic factors of non-pituitary adenomatous lesions arising from sella turcica Methods: Thirteen cases of non-pituitary adenomatous disease were treated by trans-sphenoidal microsurgery Five patients were males, 8 females With the age ranging from 33 to 66 years Among them, 9 were Rathke′s cleft cyst, 2 hypophysitis,1 primary pituitary abscess and 1 primary pituitary papilloma Results: Clinical symptoms resolved or disappeared in some extent There were no complication, recurrence or death found in 4 months to 3 5 years follow up Conclusion: Non-pituitary adenomatous disease of pituitary may be confused with pituitary adenoma, but historical information is most important in diagnosis Brain MRI may be helpful to differentiate other diseases Trans-sphenoidal surgery is the best choice in treatment of this disease