异丙酚和硫喷妥钠对琥珀胆碱肌松效应的对比研究

Comparative Study of Neuromuscular Effects of Propofol or Thiopental on Succinylcholine

目的 :对比研究异丙酚和硫喷妥钠对琥珀胆碱肌松效应的影响。方法 :34例拟行喉显微手术病人随机分为两组 ,分别给予异丙酚或硫喷妥钠静脉复合麻醉。全麻诱导后 ,静注琥珀胆碱 1 5mg/kg后气管插管 ,继之连续静滴 0 1%琥珀胆碱溶液维持肌松状态至术毕 ,以加速度仪监测。结果与结论 :与硫喷妥钠组相比 ,异丙酚麻醉时琥珀胆碱的肌松起效更快 。

Objective: To investigate the neuromuscular effects of propofol or thiopental on succinylcholine.Methods:34 adult patients schedulled for laryngomicrosurgery were anesthetized by either propofol or thiopental.After induction,the trachea was intubated with sccinylcholine 15mg/kg,and muscular relaxation was maintained with 01% succinylcholine infusion.Neuromuscular effects were monitored by accelerography.Results and Conclusion:The onset time and recovery index of succinylcholine in propofol group were less than that in thiopental group.