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肝癌患者血浆游离DNA检测的意义 被引量:2

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摘要 近年,血浆游离DNA(cell-free DNA,cfDNA)受到越来越多的关注。新近一期《Science》杂志专门刊登编辑文章强调cfDNA可能是血液中的潜在的生物标志物[1]。cfDNA的检测就如"液态的组织活检(liquid biopsy)",有可能代替现在的肿瘤活组织检查[2]。研究表明cfDNA浓度在肿瘤患者中升高[3],且随肿瘤大小、部位以及严重程度而不同。
机构地区 兴山县人民医院
出处 《中国实验诊断学》 2012年第2期308-310,共3页 Chinese Journal of Laboratory Diagnosis
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参考文献9

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同被引文献20

  • 1Waqar K.Saeed,Dae Won Jun.Viewpoint: necroptosis influences the type of liver cancer via changes of hepatic microenvironment[J].Hepatobiliary Surgery and Nutrition,2019,8(5):549-551. 被引量:1
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  • 5Spindler KL, Pallisgaard N, Vogelius I, et al. Quantitative cell-free DNA, KRAS, and BRAF mutations in plasma from patients with metastatic colorectal cancer during treatment with cetuximab and irinotecan[J]. Clinical Cancer Research, 2012,18(4) : 1177-1185.
  • 6Yu S, Wu J, Xu S, et al. Modified PNA-PCR method: a convenient and accurate method to screen plasma KRAS mutations of cancer patients[J]. Cancer Biology , Therapy, 2012,13(5) ,314-320.
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