参附注射液治疗慢性收缩性心力衰竭疗效观察

Clinical Obersevation of Shenfu Injection on Chronic Systolic Heart Failure

目的:观察参附注射液对慢性收缩性心力衰竭患者的临床疗效。方法:将患者100例随机分为对照组与治疗组各50例,均予常规西医治疗,治疗组加用参附注射液静点;比较两组治疗后心功能、无创血流动力学指标、血浆BNP水平及心脏彩超EF值的变化。结果:治疗组心功能、无创血流动力学指标(CO、SV、ACI、SVR、TFC)、血浆BNP水平和心脏彩超EF值改善均优于对照组。结论:参附注射液显著改善慢性收缩性心力衰竭患者心脏的血流动力学指标,增强心脏的收缩功能,增加心输出量,提高射血分数,降低血浆BNP浓度。

Objective： To evaluate the clinical effect of chronic systolic heart failure treated by Shenfu injection. Method： 100 patients were divided into two groups randomly.The control group was treated by conventional treatment,including diuretics etc.In addition to the conventional treatment as same as the control group,the treatment group received Shenfu injection once a day.The heart function,B-type natriuretic peptide and impedance cardiography were measured before and after treatment. Result： After the treatment,both groups could improve heart failure symptom in different degrees.There were more improvemeants in the treatment group than that in the control group. Conclusion： The heart function parameters and the clinical effect of the chronic systolic heart failure with Shenfu injection combined routine therapy are markly improved.