摘要
目的:检测老年多器官功能不全综合征(MODSE)患者的细胞免疫、体液免疫指标,了解其免疫水平及其与疾病的关系。方法:将老年患者根据诊断分为MODSE组(46例)和对照组(40例),用双/三色直接免疫荧光标记全血溶血法检测细胞免疫CD3^+、CD3^+CD4^+、CD3^+CD8^+、CD4^+/CD8^+、NK、CIK指标;用免疫比浊法检测体液免疫C3,C4,CH50,IgG,IgA,IgM指标。结果:两组患者CD3^+,NK,IgA差异有统计学意义(P<0.05)。两组免疫功能比较有明显差异:对照组CD3^+高,MODSE组NK、IgA高。结论:MODSE组患者存在免疫功能低下。
Objective To study the corraletion between the level of immunity and diseases through detecting the indices of cel- lular immunity and humoral irmnunity of MODSE. Methods A total of 86 patients were divided into the group of MODSE (46 cases) and the group of antitheses(dO cases) according to the results of diagnoses . Double-colored/tri-colored iinmunofluorescence sign the whole blood hemolysis were used to determine CD3 + , CD3 + CD4 + , CD3 + CD8 + , CD4 +/CD8 + , NK, CIK; The concentration of C3, CA, CHS0,IgG,IgA,IgM were measured by ITM immunoturbidimetry . Results Compared with the antitheses group of in the MODSE group, the levels of NK and IgA increased , the contents of CD3 + declined. Conclusion The level of immunity decreased in the MODSE group.
出处
《放射免疫学杂志》
CAS
2012年第1期71-73,共3页
Journal of Radioimmanology
关键词
免疫功能
细胞免疫
体液免疫
多器官功能不全综合征
immunity,cellular immunity,humoral immunity,multiple organ disfunction syndrome(MODS)