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老年多器官功能不全综合征患者免疫功能探讨 被引量:1

Study on the Immunofunction in Eldery Patients with Multiple Organ Disfunction Syndrome
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摘要 目的:检测老年多器官功能不全综合征(MODSE)患者的细胞免疫、体液免疫指标,了解其免疫水平及其与疾病的关系。方法:将老年患者根据诊断分为MODSE组(46例)和对照组(40例),用双/三色直接免疫荧光标记全血溶血法检测细胞免疫CD3^+、CD3^+CD4^+、CD3^+CD8^+、CD4^+/CD8^+、NK、CIK指标;用免疫比浊法检测体液免疫C3,C4,CH50,IgG,IgA,IgM指标。结果:两组患者CD3^+,NK,IgA差异有统计学意义(P<0.05)。两组免疫功能比较有明显差异:对照组CD3^+高,MODSE组NK、IgA高。结论:MODSE组患者存在免疫功能低下。 Objective To study the corraletion between the level of immunity and diseases through detecting the indices of cel- lular immunity and humoral irmnunity of MODSE. Methods A total of 86 patients were divided into the group of MODSE (46 cases) and the group of antitheses(dO cases) according to the results of diagnoses . Double-colored/tri-colored iinmunofluorescence sign the whole blood hemolysis were used to determine CD3 + , CD3 + CD4 + , CD3 + CD8 + , CD4 +/CD8 + , NK, CIK; The concentration of C3, CA, CHS0,IgG,IgA,IgM were measured by ITM immunoturbidimetry . Results Compared with the antitheses group of in the MODSE group, the levels of NK and IgA increased , the contents of CD3 + declined. Conclusion The level of immunity decreased in the MODSE group.
出处 《放射免疫学杂志》 CAS 2012年第1期71-73,共3页 Journal of Radioimmanology
关键词 免疫功能 细胞免疫 体液免疫 多器官功能不全综合征 immunity,cellular immunity,humoral immunity,multiple organ disfunction syndrome(MODS)
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  • 1王士雯.老年重症多器官衰竭55例临床分析[J].解放军医学杂志,1987,12(5):340-340.
  • 2王士雯,王今达,陈可冀,王一镗,王新德,牟善初.老年多器官功能不全综合征(MODSE)诊断标准(试行草案,2003)[J].中国危重病急救医学,2004,16(1):1-1. 被引量:227
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