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结肠癌合并2型糖尿病患者胰岛素样生长因子-I表达与淋巴结转移的关系 被引量:2

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摘要 [目的]探讨结肠癌合并2型糖尿病(T2DM)患者胰岛素样生长因子-I(IGF-I)表达与淋巴结转移的关系.[方法]采用免疫组织化学方法检测38例结肠癌合并T2DM患者和单纯结肠癌患者结肠癌组织中IGF-I表达情况.[结果]结肠癌合并T2DM患者组IGF-I阳性表达率(71.43%)明显高于无糖尿病组(DM)(47.22%)( P 〈0.05).有淋巴结转移者占IGF-I阳性表达者中60.6%(20/33),显著高于IGF-I阴性表达中有淋巴结转移者的比例(37.5%,9/24).[结论]T2DM可能增加结肠癌淋巴结转移几率.
出处 《医学临床研究》 CAS 2012年第1期153-154,共2页 Journal of Clinical Research
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