2000例妇女宫颈人乳头瘤病毒普查结果分析

Analysis on the results of general investigation about cervical human papillomavirus among 2 000 women

目的:了解妇女宫颈人乳头瘤病毒感染及感染类型。方法:选取参与普查的2 000例妇女为研究对象,在告知受检者实验目的并得到同意的情况下,使用HC-2的检验方式对受检者进行宫颈刮片并对结果进行HPV的DNA检测以确定受检者HPV类型。结果:普查的2000例受检者中检测出HPV感染者一共832例,占普查总人数的41.60%,而在检出的832例感染者中,高危型HPV者617例,占HPV感染总人数的74.16%,低危型HPV感染者占总感染人数的25.84%。单发感染占53.73%,多发感染占46.27%。结论:该次普查结果中发现HPV-16、18、33、56、58的检测阳性率明显多于其他,这与目前外界报道研究结果相符合;广大妇女应定时的进行HPV测定,以及时纠正宫颈病变和预防宫颈癌的发生。

Objective： To understand the prevalence and types of cervical human papillomavirus （HPV） among 2 000 women. Methods： A total of 2 000 women who participated in the general investigation were selected as study objects, HC - 2 method was used for cervical scraping smear according to the principle of informed consent, then HPV DNA detection was performed to confirm the types of HPV. Results ： Among 2 000 women who participated in the general investigation, 832 women were found with HPV infection, accounting for 41.60% , including 617 women with high risk HPV infection （74. 16% ） and 215 women with low risk HPV infection （25.84%） . The women with single infection and multiple infection accounted for 53.73% and 46. 27% , respectively. Conclusion： During the general inves- tigation, the positive detection rates of HPV 16, 18, 33,56, and 58 are significantly higher than those of other types of HPV, which is consistent with the current research findings reported in the outside world; the women should receive HPV detection regularly, in order to correct cervical lesions and prevent the occurrence of cervical cancer.