银杏达莫注射液在急性脑梗死的应用

The Observation of Aplication of Ginkgo Leaf Extract and Diphyridamole Injection in the Treatment of Acute Cerebral Infarction

目的:探讨银杏达莫注射液对急性脑梗死的治疗效果。方法:急性脑梗死患者108例,随机分为观察组与对照组各54例,观察组给予银杏达莫注射液,对照组给予复方丹参注射液,剂量均为20 mL加入生理盐水250 mL,gtt,1次/d,连续2周。对比两组神经功能缺损评分、有效率、血液流变学指标以及不良反应情况。结果:两组治疗后神经功能缺损评分较治疗前均显著降低(P<0.05或P<0.01),且治疗后观察组显著低于对照组(P<0.01);观察组总有效率为88.9%,显著高于对照组的72.2%(P<0.05);两组患者全血黏度、血浆黏度以及血小板聚集率均较治疗前显著降低(P<0.05或P<0.01),且治疗后观察组3项指标均显著低于对照组(P<0.05或P<0.01);治疗过程中两组均未出现严重不良反应。结论:银杏达莫注射液对于急性脑梗死的治疗效果确切,毒副作用较少,值得推广应用。

Objective：To observe the effect of ginkgo leaf extract and diphyridamole injection in the treatment of acute cerebral infarction.Method：One hundred and eight patients with acute cerebral infarction were randomly devided into observation group（54patients） and control group（54 patients）,the observation group were given ginkgo leaf extract and diphyridamole injection,and the control group were given compound danshen injection,The Neurdogical Funtional Deficit Scores（NFDS）,effective rate,hematological indexes,and the adverse reaction between the two groups were observed.Result： The NFDS of the two groups was significantly lower than before（P0.05 or P0.01）,and the observation group was significantly lower than control group after treatment（P0.01）;the total effective rate of the observation group（88.9%） was significantly higher than that in the control group（72.2%）（P0.05）;the hematological indexes of the two groups were significantly lower than before（P0.05 or P0.01）,and the observation group was significantly lower than control group after treatment（P0.05 or P0.01）;there was no severe adverse reactions during the theatment.Conclusion： The theatment of Ginkgo leaf extract and diphyridamole injection is effective,and with less side effects in the treatment for acute cerebral infarction.