脱细胞异体真皮基质填塞治疗肛瘘的临床体会

Clinical study on anal fistula treatment with acellular extracellular matrix

目的探讨脱细胞异体真皮基质填塞治疗肛瘘的临床疗效。方法采用脱细胞异体真皮基质填塞治疗12例肛瘘患者,观察其临床效果。结果本组患者瘘管愈合时间7～18d,平均(13.0±3.3)d。12例患者中治愈9例,治愈率为75%,失败3例,随访6个月复发1例,复发率为8.3%。本组无肛门失禁、肛门畸形发生。结论脱细胞异体真皮基质填塞治疗肛瘘具有创伤小、疼痛轻、恢复快、不损害肛门功能和外形的优点,但远期效果需进一步观察。

Objective To observe the effects of the efficacy of acellular extracellular matrix （AEM） treatment for anal fistula. Methods Twelve patients with anal fistula were treated with AEM. The clinical effects were observed, Results Nine cases were cured, but 3 failed and 1 case relapsed after 6 months. The heal rate of anal fistula was 75%. Conclusions This method has advantages of mild traumas and less pain, rapid recovery rapidly, and the most important is that this treatment could protect anal function and appearance. However, the long-term effect needs further study.