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前列地尔脂微球制剂对犬肝动脉碘油栓塞后的保护作用

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摘要 目的:探讨前列地尔脂微球制剂(Lipo-PGEl)对犬肝动脉栓塞后的保护作用。方法:将动物随机分为三组,肝动脉内注入生理盐水为空白组(A组),肝动脉内注入碘化油为对照组(B组),肝动脉内注入碘化油+前列地尔为治疗组(c组),观察丙氨酸氨基转移酶(Alanine aminotransferase,ALT)、天冬氨酸转移酶(Aspartate aminotransferase,AST)及乳酸脱氢酶(Lactatedehydrogenase,LDH)等指标,肝组织病理检查。结果:治疗组各项生化指标高于生理盐水组,但低于碘化油组。病理学检查治疗组肝组织坏死较碘化油组轻。结论:Lipo—PGEl能改善肝动脉碘油栓塞后的肝功能。
出处 《中国中医药咨讯》 2012年第1期43-44,共2页
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