细胞粘附分子与肝脏移植排斥反应

Cell Adhesion Molecules in Liver Allograft Rejection

同种移植排斥至今仍是器官移植后一个尚未完全解决的难题 ,也是移植失败的主要原因。近年来 ,许多学者研究证实 :细胞粘附分子在肝脏同种移植排斥反应中起到至关重要的作用。综述了细胞粘附分子的生物学特点。

The allograft rejection is still a challenge to transplantation surgeon and remains the major cause of graft loss Recent research has shown that cell adhesion molecules(CAMs) play a predominant role in liver allograft rejection The article summarizes CAMs biological features, their induction and expression in liver allograft rejection and new diagnostic options and therapeutic strategies