间接免疫过氧化酶联A蛋白试验对阿米巴肝脓肿诊断价值的探讨

THE VALUE OF INDIRECT IMMUNOPEROXIDASE PROTEIN A TEST IN THE DIAGNOSIS OF AMEBIC LIVER ABSCESS

本文采用间接免疫过氧化酶联A蛋白试验(IIPA)对55例阿米巴肝脓肿患者和100例对照组(原发性肝癌患者、健康人各50例)的血清进行了阿米巴抗体的检测.结果为:阿米巴肝脓肿55例患者的血清全部阳性,阳性率100%,阳性滴度多数在1∶160～1∶640(占80%),最高达到1∶5120;50名原发性肝癌患者和50名健康献血员的血清全部阴性;IIPA的平均几何滴度与间接荧光抗体试验(IFA)的平均几何滴度相比,无明显差别(P>0.1).说明该法在诊断阿米巴肝脓肿上有高度的特异性和敏感性.

Indirect immunoperoxidase protein A test(IIPA) was performed in the sera of 55 cases of amebic liver abscess (ALA) and in 100 control sera (including 50 cases of primary liver cancer and 50 normal healthy subjects).The IIPA was positive in all 55 ALA cases.The positive rate was 100%.In 80% of these cases, the titer of IIPA antibody ranged from 1∶160 to 1∶640.The highest titer being 1: 5120.No false positive result was found in those 100 controls.The results demonstrated that this test was simple,quick and reliable in establishing the etiological diagnosis of amebic liver abscess.