肺炎支原体肺炎患者使用抗菌药分析

Analysis of Antibacterial Drugs Application in the Patients with Mycoplasma Pneumonia

目的:了解本院肺炎支原体肺炎患者使用抗菌药的情况。方法:回顾性调查2010年收住呼吸科的97例肺炎支原体肺炎患者使用抗菌药的种类、频率、疗程、联合用药、治愈率、药品不良反应发生率,并根据《抗菌药物临床应用指导原则》和《社区获得性肺炎诊断和治疗指南》对其用药合理性进行评价。结果:抗菌药使用率达100%,诊断前后的合理率分别为35.0%和50.5%;共涉及6大类21个品种,使用前5种分别是莫西沙星、阿奇霉素、阿洛西林、头孢他啶、头孢地嗪;联合用药以二联为主;超疗程占91.7%;用法用量不合理占4.1%。治愈率为66.0%。结论:本院肺炎支原体肺炎的抗菌药使用还存在一些不合理现象,需加强监管,严格按照治疗指南,规范合理应用。

Objective： To analyze the usage of antibiotics in the patients with mycoplasmal pneumonia in Ruian People＇ s Hospital. Method： According to the ＂Guidelines for Clinical Use of Antibiotics＂ and ＂Diagnosis and Treatment Guidelines for Community-acquired Pneumonia＂, the types, application frequency, course of treatment, combination, cure rate and adverse drug reactions of antibiotics were statistically analyzed by the retrospective investigation in 97 patients with myeoplasma pneumonia in the year of 2010. Result： In the 97 cases,the percent of antibiotics usage was 100% with the reasonable rate before and after diagnosis of 35.0% and 50. 5% ,respectively. The used antibiotics included 6 categories and 21 species. Among them, the first 5 were moxifloxacin, azithromycin, azloeillin, cefiazidime and cefodizime. Two-kind drug combination was the main combination therapy. The percent of over-course treatment was 91.7%. The ratio of unreasonable usage was 4. 1%. The cure rate was 66. 0%. Conclusion： There is irrational application of antimicrobial drugs in the patients with mycoplasma pneumonia. It is necessary to strengthen the supervision and enhance the rational use of antibiotics according to the guidelines.