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联合内外减压术治疗颅脑损伤合并脑疝的临床研究 被引量:18

Clinical study on the effect of combined decompression operation on brain injury complicated with cerebral herniation
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摘要 目的探讨联合内外减压术治疗重型颅脑损伤合并脑疝的手术效果。方法将95例重型颅脑损伤合并脑疝患者随机分为两组,治疗组47例采用联合内外减压术治疗,对照组48采用标准大骨瓣开颅减压术治疗。结果治疗组恢复良好23例、中残9例、重残6例、植物生存3例、死亡6例;对照组恢复良好14例、中残6例、重残9例、植物生存4例、死亡15例;两组生存质量和病死率差异具有统计学意义(P<0.05)。两组患者术后影像学表现、并发症发生率比较差异具有统计学意义(P<0.05)。结论运用联合内外减压术治疗重型颅脑损伤合并脑疝患者能显著提高疗效,降低病死率及并发症。 Objective To explore the effect of combined decompression operation on severe brain injury complicated with cerebral herniation. Methods Ninety-five patients with severe brain injury complicated with cerebral herniation were randomly divided into two groups: treatment group (n = 47 ), on whom combined decompression operation was performed, and control group (n = 48 ), on whom standard big bone flap crainiectomy decompression was performed. Results 23 patients of the treatment group recovered well; 9 patients suffered from moderate disability; 6 patients experienced severe deficits; 3 patients were vegetative and 6 patients died after the operation. Comparatively, only 14 patients of the control group recovered well; 6 patients suffered from moderate disability; 9 patients experienced severe deficits; 4 patients were vegetative and as many as 15 patients died after the operation. Levels of the survival quality and death rate of the former group were significantly higher than that of the later group ( P 〈 0.05 ). Besides, the levels of the imageological features and complication rates of the former group after operation were also ignificantly higher than that of the later group ( P 〈 0.05 ). Conclusion The combined decom-pression operation has a significant effect on curing severe brain injury complicated with cerebral herniation and reducing death rate and complication rate.
出处 《临床神经外科杂志》 CAS 2011年第6期318-320,共3页 Journal of Clinical Neurosurgery
基金 福建省卫生厅青年科研课题(2007-1-8)
关键词 重型颅脑损伤 脑疝 联合减压术 severe brain injury cerebral herniation combined decompression operation
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