摘要
目的:探讨齐拉西酮与利培酮治疗精神分裂症的疗效和安全性。方法:将85例精神分裂症患者随机分为齐拉西酮组和利培酮组,进行为期8周的双盲对照研究。采用阳性与阴性症状量表(PANSS)和治疗中出现的症状量表(TESS)评定疗效和不良反应。结果:齐拉西酮有效率为80.2%,利培酮有效率为83.5%,二者差异无显著性。结论:齐拉西酮治疗精神分裂症疗效较好,与利培酮相当,但不良反应有所不同。
Objective: To evaluate the efficacy and side effect of ziprasidone and resperidone in the treatment of schizophrenia. Method:Eighty - five patients with schizopherenia were randomly divided into ziprasidone groups (n = 42) and resperidone group (n = 43) for 8 weeks. Both groups were assessed with the positive and negative symptoms scale (PANSS) and treatment emergent symptoms scale(TESS) to evaluate their efficacy and side effect. Results: Two drugs had similar efficacy in the treatment of schizophrenia . The response rate of ziprasidone is 80.2 % and of resperidone is 83.5 %. Conclusion. Ziprasidone is an effective antipsychotic drugs and have same efficacy with resperidone in the treatment of schizophrenia.
出处
《内蒙古医学杂志》
2011年第11期1321-1323,共3页
Inner Mongolia Medical Journal