双源螺旋CT冠状动脉造影诊断冠心病合并糖尿病多支冠状动脉病变的临床价值

Clinical investigation of coronary artery disease patients with multi vessel disease and type 2 diabetes evaluated by dual-source computed tomography coronary angiography

目的:探讨双源螺旋CT冠状动脉造影(DSCTA)诊断冠心病(CHD)合并糖尿病患者多支冠状动脉病变的价值。方法:对48例CHD合并糖尿病患者进行DSCTA和冠状动脉造影(CAG)检查,以CAG结果为金标准,比较DSCTA与CAG对冠状动脉多支病变严重程度的差异。结果:48例患者中,DSCTA成像诊断多支冠状动脉病变的敏感性、特异性、阳性预测值、阴性预测值分别为91.91%、100.00%、100.00%、94.72%;2种方法对冠状动脉病变严重性比较差异有统计学意义(P<0.01),DSCTA与CAG在诊断CHD合并糖尿病患者冠状动脉狭窄程度方面有显著相关关系(P<0.01)。结论:DSCTA对CHD合并糖尿病患者多支冠状动脉病变能作出可靠诊断。

Objective：To assess the clinical value of dual-source computed tomography coronary angiography（DSCTA） in diagnosing coronary heant disease（CHD） patients with multi vessel disease and type 2 diabetes.Methods：Forty-eight patients suffering from coronary artery disease and type 2 diabetes were underwent both DSCTA and coronary angiography（CAG）.Regarding CAG as a standard reference,50% stenosis in two or more than two major coronary arteries were as multi vessel disease,the reliability of DSCTA for diagnosing coronary stenosis was analyzed.Results：In the forty-eight patients,compared with CAG,the sensitivity and specificity of DSCTA for detecting light,middle and severe multivessel disease were 91.91%,100.00%,100.00%,94.72%,respectively.Conclusions：DSCTA could reliably provide promising value of diagnosing multi vessel disease in CHD patients with type 2 diabetes.