超敏C反应蛋白和心房颤动的关系

Relationship between high sensitivity C reactive protein and atrial fibrillation

目的:观察心房颤动患者超敏C反应蛋白(hs-CRP)水平变化,探讨炎症与心房颤动的关系。方法:将84例心房颤动患者分为持续性心房颤动组(>30 d)43例和阵发性心房颤动组(<48 h)41例,并选择40例水平窦性心律者作为对照组。采用酶联免疫双抗体夹心法测定hs-CRP。结果:持续性心房颤动组患者血清hs-CRP水平高于阵发性心房颤动组和对照组(P<0.01),阵发性心房颤动组患者血清hs-CRP水平高于对照组(P<0.01)。结论:心房颤动与炎症有关,炎症参与了心房颤动的发生和持续。

Objective：To observe the change of high sensitivity C-reactive protein（hs-CRP） in patients with atrial fibrillation so as to explore the correlation between inflammation and atrial fibrillation.Methods：Eighty-four patients with atrial fibrillation were divided into two groups：persistent atrial fibrillation（30 days） group（43 cases） and paroxysmal atrial fibrillation（48 hours）group（41 cases）,and 40 patients with sinus rhythm acted as control.The serum hs-CRP content of each group was measured by enzyme linked immunosorbent assay.Results：The serum level of hs-CRP in the persistent atrial fibrillation group was higher than that in the paroxysmal atrial fibrillation group and the control group（P0.01）;the serum level of hs-CRP content in the paroxysmal atrial fibrillation group was higher than that in the control group（P0.01）.Conclusions：The result indicates that inflammation may play an important role in the genesis and sustaining of atrial fibrillation.