期刊文献+

宫颈环形电切术治疗宫颈上皮内瘤样变Ⅱ~Ⅲ级的临床分析

下载PDF
导出
摘要 目的探讨宫颈环形电切术(LEEP)在治疗宫颈上皮内瘤样变(CIN)的临床分析,以期对高级别CIN的诊断及治疗提供一定的临床经验,达到早期预防宫颈癌变的目的。方法对阴道镜下多点活检术后病理诊断为CIN Ⅱ~Ⅲ级的98例患者采用LEEP术进行治疗,对其疗效、并发症、复发情况做回顾性分析。结果手术时间平均13.5min,术中出血量平均15ml。手术前后宫颈环切组织病理结果比较、病变分级一致者64例(65.31%),级别下降者26例(26.53%),级别上升者8例(8.16%)。CIN治愈95例(96.94%),病变残留2例(2.04%),病变复发1例(1.02%)。结论 LEEP术是治疗CINⅡ~Ⅲ级安全有效的方法,其术后并发症少,病变残留复发率低。
作者 严菊兰
机构地区 上虞市人民医院
出处 《现代实用医学》 2011年第12期1395-1397,共3页 Modern Practical Medicine
  • 相关文献

参考文献5

二级参考文献24

  • 1Sarian LO, Derchain SF, Andrade LA, et al. HPV DNA test and Pap smear in detection of residual and recurrent disease following loop electrosurgical excision procedure of high-grade cervical intraepithelial neoplasia. Gynecol Oncol, 2004,94 : 181-186.
  • 2Numnum TM, Kirby To, Leath CA 3rd, et al. A prospective evaluation of "see and treat" in women with HSIL . Pap smear results : is this an appropriate strategy? J Low Genit Tract Dis, 2005,9:2-6.
  • 3Livasy CA, Maygarden SJ, Rajaratnam CT, et al. Predictors of recurrent dysplasia after a cervical loop electrocautery excision procedure for CIN-3: a study of margin, endocervical gland, and quadrant involvement . Mod Pathol, 1999,12 : 233-238.
  • 4Reich O, Pickel H, Lahousen M, et al. Cervical intraepithelial neoplasia Ⅲ: long-term outcome after cold-knife conization with clear margins. Obstet Gynecol, 2001,97:428-430.
  • 5Kang SB, Roh JW, Kim JW, et al. A comparison of the therapeutic efficacies of large loop excision of transformation zone and hysterectomy for the treatment of cervical intraepithelial neoplasia Ⅲ.Int J Gynecol Cancer, 2001,11:387-391.
  • 6Corona Gutierrez CM, Tinoco A, Navarro T, et al. Therapeutic vaccination with MVAE2 can eliminate precancerous lesions associated with infection by oncogenic human papillomavims. Human Gene Ther, 2004, 15:421-431.
  • 7Yamaguchi S, Tsuda H, Takemori M, et al. Photodynamic therapy for cervical intraepithelial neoplasia. Ontology, 2005,69 : 110-116.
  • 8Bodner K, Bodner-Adler B, Wierrani F, et al. Cold-knife conization versus photodynamic therapy with topical 5-aminolevulinic acid in cervical intraepithelial neoplasia Ⅱ with associated human papillomavirus infection: a comparison of preliminary results.Anticancer Res, 2003, v23 (2C) : 1785-1788.
  • 9Benedet JL, Miller DM, Nickerson KG. Results of conservative management of cervical intraepithelial neoplasia. Obstet Gynecol,1992, 79:105-110.
  • 10Nuovo J, Melnikow J, Willan AR, et al. Treatment outcomes for squamous intraepithelial lesions. Int J Gynaecol Obstet, 2000, 68:25 -33.

共引文献556

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部