短暂性脑缺血发作发展至脑梗死危险因素的临床意义

The clinical significance of risk factors for development from transient ischemic attack to cerebral infarction

目的:对短暂性脑缺血发作(transient ischemic attack,TIA)患者发展至出现脑梗死的相关危险因素进行探讨。方法:回顾2007年10月～2009年6月本科收治的100例TIA患者临床资料,经2010年回访获悉,其中40例发生脑梗死。结果:患者TIA的发作时间大于30min,并且24h内发作大于3次,和首次发作后大于24h,并且发作大于5次的患者患脑梗死危险性明显提高(P<0.05)。而发生脑梗死40例TIA患者其血压与血糖以及总胆固醇均明显增高(P<0.05)。结论:如果每次TIA发作的持续时间较长,并且次数较多,未予及时治疗,特别是伴高血压与高血糖以及高脂血症的患者,极易于短期内发生脑梗死,临床应高度重视。

Objective： To investigate risk factors for development from transient ischemic attack（TIA） to cerebral infarction. Methods： Clinical data of 100 cases of TIA patients in our hospital from October 2007 to June 2009 were analyzed, of which 40 cases developed to cerebral infarction. Results： Risk of TIA patients of which onset time was longer than 30 minutes and onset more than 3 times in 24 hours, attack more than 5 times in 24 hours after the first attack, and the suffering from cerebral infarction significantly improved （P〈0.05）. The blood pressure and blood sugar and total cholesterol of 40 cases of TIA patients with cerebral infarction were significantly higher （P〈0.05）. Conclusion： TIA patients with long onset time, high frequency, no timely treatment can develop to cerebral infarction in short term, especially in patients with hypertension, hyperlipidemia and hyperglycemia, clinician should pay more attention to these patients.