血液灌流对急性百草枯中毒的疗效研究

The curative effect of blood perfusion on acute paraquat poisoning

目的:研究急性百草枯中毒采用血液灌流治疗的临床特点及疗效。方法:将57例急性百草枯中毒患者分为血液灌流治疗组与非血液灌流治疗组(一般治疗与药物治疗)。对患者的一般情况进行总结,包括中毒量、首次X线正常例数、首次动脉血氧分压。结果:血液灌流组5d内出现两肺弥漫性病变15例,呼吸衰竭14例,出院好转13例;非血液灌流组5d内出现两肺弥漫性病变24例,呼吸衰竭22例,出院好转2例,两组比较差异均有统计学意义(P<0.05)。结论:血液灌流治疗急性百草枯中毒的效果明显,在临床上应及早使用,以提高治愈率,同时降低死亡率。

Objective： To study clinical features and efficacy of acute paraquat poisoning using hemoperfusion. Methods： Fifty seven patients with acute paraquat poisoning patients patients were divided into hemoperfusion blood perfusion group and the blood perfusion treatment group （general treatment and drug treatment）. The general condition of the patient was summaried, including toxic dose, for the first time X-ray normal number of cases, the first arterial oxygen partial pressure. Results： Blood perfusion group 5 days occured lungs diffuse lesions 15 cases, respiratory failure 14 cases, hospital discharged improved 13 cases; non-blood perfusion group five days occured lungs diffuse lesions 24 cases, respiratory failure 22 cases, hospital discharged improved 2 cases, differences were statistically significant of two groups （P〈0.05）. Conclusion： Hemoperfusion treatment of acute paraquat poisoning effect is obvious, in clinical use should be early, in order to enhance the curative rate, at the same time, reduce mortality.