沈阳地区变应性鼻炎变应原皮肤点刺试验结果分析与临床意义

Result analysis and clinical significance of allergen skin prick test on patients with allergic rhinitis in Shenyang area

目的了解沈阳地区变应性鼻炎患者皮肤点刺实验(SPT)阳性率、致敏原及SPT的临床意义。方法对1 015例拟诊断为变应性鼻炎的患者采用12组致敏原(ALK公司)实施皮肤点刺试验。结果 1 015例患者中有619例对致敏原至少有一组呈现阳性反应(61%),阳性率相对较高的的变应原依次是粉尘螨(75.0%)、屋尘螨(71.1%)、艾蒿(56.2%)、豚草(42.0%)等,男女之间比较差异无统计学意义(P>0.05)。结论沈阳地区变应性鼻炎患者SPT阳性率男女之间阳性率无明显差异。螨及艾蒿、豚草是主要的的致敏原。

[Objective ] To find out the positive rate of Skin Prick Test （SPT） on patients with allergic rhinitis, its allergens and clinical significance of SPT. [Methods] SPT is conducted on 1,015 patients diagnosed with allergic rhinitis by using 12 pairs of allergens （ALK）. [Results] It is found that 619 subjects a- mong the total showed positive reactions towards at least one pair of allergens （61%）. Allergens with compara- tively higher positive rate are dermatophagoides farinae （75.0%）, dermatophagoides ptoronyssinus （71.1%）, mugwort （56.2%）, ragweed （42.0%）. It is also found that comparison between male and female patients has no statistic significance （P〉0.05）. [ Conclusion] The results indicates that allergens SPT on patients with allergic rhinitis exerts no obvious difference on the positive rate between male and female patients in Shenyang area, and the key allergens are acarid, mugwort and ragweed.