含头孢羟氨苄的三联方案根除幽门螺杆菌疗效观察

A Study on the Effect of Cefadroxil-centered Triple Therapy on Helicobacter Pylori Eradication

目的观察以头孢羟氨苄为中心的三联方案根除幽门螺杆菌(HP)的效果。方法 102例幽门螺杆菌感染的患者随机分为3组,每组34人。A组采用雷贝拉唑肠溶胶囊、替硝唑片、克拉霉素片治疗;B组采用雷贝拉唑肠溶胶囊、替硝唑片、头孢羟氨苄胶囊治疗;C组(对照组)采用雷贝拉唑肠溶胶囊、替硝唑片治疗。疗程为10 d,治疗结束后复查幽门螺杆菌根除情况。结果 A组HP根除率为74%,B组HP根除率为97%,C组根除率为35%。结论以头孢羟氨苄为中心的三联疗法根除幽门螺杆菌具有疗效好、耐药性低等特点,较传统方案更有优势。

Objective To observe the effect of Cefadroxil-centered triple therapy on Helicobacter Pylori（HP） eradication.Methods 102 patients with HP were randomly classified into three groups,each group including 34 patients.Rabeprazole enteric-coated capsules,tinidazole tablets and clarithromycin tablets were adopted in treating the patients in Group A,Rabeprazole enteric-coated capsules,tinidazole tablets and Cefadroxil capsule in Group B,Rabeprazole enteric-coated capsules and tinidazole tablets in Group C as the control group.After the therapy of 10 days,eradication of the HP was examined.Results The rate of HP eradication was 74 percents in Group A,97 percents in Group B,35 percents in Group C.Conclusion It is effective,low-resistant and much better than the traditional therapy to eradicate HP with the Cefadroxil-centered triple therapy.