临床分离的129株鲍曼不动杆菌的耐药性分析

Analysis of clinical distribution and drug resistance of the Bauman acinetobacter

目的:了解鲍曼不动杆菌的耐药和临床分布情况,为防控医院感染提供依据。方法:对129株鲍曼不动杆菌的临床分布和常用抗菌药物的耐药情况进行分析。结果:痰标本检出率最高,为72.09%;患者主要分布在内科和重症监护治疗病房;分离出的129株鲍曼不动杆菌仅有3种药物耐药率<30%,分别是亚胺培南(24.80%)、哌拉西林/他唑巴坦(26.35%)、氨苄西林/舒巴坦(27.9%),其余药物耐药率均>50%。结论:鲍曼不动杆菌多重耐药严重,应加强耐药性监测,了解耐药变迁,为临床用药提供依据。

Objective ：To explore the drug resistance and clinical distribution of Bauman acinetobacter, and provide a basis for controlling hospital infection. Methods： The clinical distribution, drug resistance and sample separation of 129 strains of Bauman acinetobacter were analysed, and the resistance rate of 14 kinds of commonly used antimicrobial agents were calculated. Results：Sputum specimen＇s detection rate with 72.09% was highest,patients came mainly from physicians and intensive care treatment ward. The drug resistance rates of only 3 types of antimicrobial agents in 129 stains Bauman acinetobacter were less than 30% ,imipenem,piperacillin/tazobactam and ampicillin/Shu TAZ were 24.80% ,26.35% and 27.90% ,respectively,the others drug resistance rates were more than 50%. Conclusions ：As to the serious multi-drug resistance of Bauman acinetobacters,the resistance monitoring should be strengthened for directing clinical medication.