聚-α-甲基苯乙烯空心微球制备过程中的缺损研究

Investigation of defects on PAMS microspheres fabricated with microencapsulation method

基于二次乳化技术产生W1/O/W2双重乳液,采用乳液微封装技术制备聚-α-甲基苯乙烯(PAMS)空心微球,研究了部分工艺参数对PAMS微球缺损形态和比例的影响。实验结果表明:薄壁微球的低强度导致了微球表面缺损。当微球壁厚一定时,有3个因素影响缺损微球比例:W2相中聚乙烯醇质量分数、CaCl2质量分数和O/W2的相比,当它们分别为1.0%,1.5%,0.01时,薄壁(≤2μm)微球的缺损比例低于40%,球壳内也无气泡存在。

Poly-（α-methylstyrene） （PAMS） microspheres were fabricated with W1/O/W2 double emulsion microencapsulation method, and the effects of polyvinylalcohol （PVA） and CaCl2 weight concentrations and the O/W2 phase ratio on the percentages of defected PAMS microspheres were studied. The weight concentrations of PVA and CaCl2 and the O/W2 phase ratio in the fabrication process of PAMS microspheres were optimized. The results show that, for the three parameters being 1.0%, 1.5G, and 0.01, respectively, the percentage of the defect-free PAMS microspheres without vacuoles in the shell wall can be up to 60G.