慢性心力衰竭对肺功能的影响

Chronic heart failure of the influence of pulmonary function

目的:探讨慢性心力衰竭患者不同左室射血分数(LVEF)对肺功能的影响。方法:对58例慢性心力衰竭患者行心脏彩超及肺功能检查,根据LVEF分组,LVEF>40%为对照组,LVEF≤40%为观察组。肺功能检查指标包括FVC(用力肺活量)、FEV1(第1个1s内的用力肺活量)、FEF50(呼出肺活量50%时的用力呼气流量)3个指标占预计值的百分比,FEV1/FVC的比值。将两组数据进行统计学处理,并进行分析。结果:观察组肺通气功能指标下降明显,FVC由(71.53±6.32)%下降至(52.25±7.28)%,t=10.793;FEV1由(68.70±7.73)%下降至(47.43±5.73)%,t=11.832;FEF50由(77.20±6.49)%下降至(42.00±7.64)%,t=18.955;FEV1/FVC由(75.06±5.52)%下降至(54.14±6.80)%,t=12.907,P均<0.01,两组间比较差异有统计学意义。结论:慢性心力衰竭患者随LVEF降低,肺功能下降明显,主要表现为混合型通气功能障碍。

Objective： To explore chronic heart failure patients with different left ventricular ejection fraction （LVEF） of the influence of the pulmonary function. Methods： 58 cases of chronic heart failure patients with heart colour to exceed check and pulmonary function. According to LVEF group： LVEF〉40% as the control group, LVEF~〈40% as the observa- tion group. Lung function testing index includes FVC （forced vital capacity）, both FEV1 （the first 1 s within the forced vital capacity）, FEFs0 （breathe out 50% of the vital capacity when expiratory flow） three index was expected to account for the percent- age of value, FEV1/FVC of ratio. Two data statistics processing, and analyzed. Results： The observation group pulmonary ventilation function index down significantly, FVC by （71.53±6.32）% dropped to （52.25±7.28）%, t=10.793; FEV1 by （68.70±7.73）% dropped to （47.43＋5.73）%, t=1 1.832; FEF50 by （77.20＋6.49）% dropped to （42.00±7.64）%, t=18.955; FEV1/FVC by （75.06±5.52）% dropped to （54.14±6.80）%, t=12.907, P〈0.01, comparative differences between the two groups was statistically significant. Conclusion： Chronic heart failure patients with pulmonary function, reduce LVEF down significantly, main show is mixed type ventilation function obstacle.