摘要
目的:探讨糖尿病血清学各指标与微血管病变的关系。方法:选取本院2009年5月～2011年5月2型糖尿病(T2DM)住院患者共120例,其中合并微血管病变者为观察组共54例,余66例为对照组,对所有患者进行血脂、血糖以及血清淀粉样蛋白A(SAA)等指标测定,t检验探讨两组间各指标差异情况,单因素Logistic回归探讨其可能危险因素。结果:观察组与对照组除空腹血糖差异无明显统计学意义外,余指标差异均具有统计学意义;SAA、总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白(LDL)4个变量为微血管病变危险因素。结论:SAA、LDL等指标对糖尿病微血管病变具有早期诊断作用,通过炎症控制、血脂调节等可以改善病情,提高患者生存质量。
Objective： To investigate the associations between various serum markers and diabetic microangiopathy. Methods： From May 2009 to May 2011, 120 patients with T2DM in our hospital were divided into observation group （54 cases with diabetic＇, microangiopathy） and the control group （66 cases without diabetic microangiopathy）. The blood lipids, blood glucose and serum amyloid A （SAA） and other parameters were measured in all patients. The t test was performed to assess the differences of various parameters between the two groups, and a single factor Logistic regression was further per- formed to explore the possible risk factors. Results： There was obvious difference in terms of all parameters except for the fasting blood glucose. Besides, SAA, TC, TG and LDL were risk factors of diabetic microangiopathy. Conclusion： SAA, LDL and other indicators may play important roles in the early diagnosis of diabetic microangiopathy. Besides, the control of inflammation and blood lipid can modify the disease effectively and improve the quality of life.
出处
《中国当代医药》
2011年第34期81-82,共2页
China Modern Medicine
