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慢性非细菌性前列腺炎动物模型评析 被引量：12

Analysis of Animal Models of Chronic Nonbacterial Prostatitis
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摘要 慢性非细菌性前列腺炎是泌尿科的常见疾病之一,症状复杂,病程迁延,严重影响患者的生活质量。慢性非细菌性前列腺炎发病机制目前尚不确定,制备理想的慢性非细菌性前列腺炎动物模型对研究其发病机制和治疗药物具有重要的现实意义。本文就慢性非细菌性前列腺炎的动物模型的最新研究进展作简要综述,并对各种模型的特点进行评析。 Chronic nonbacterial prostatitis is one of the common urological diseases with complex symptomes and a long course, which seriously influence patients＇ quality of life. The pathogenesis of chronic nonbacterial prostatitis is complicated and unclear. Making ideal animal models might be useful in elucidating the mechanisms involved in the molecular pathogenesis of chronic nonbacterial prostatitis and exploiting new therapeutic drugs. Therefore, in this review, the current knowledge regarding animal models of chronic nonbacterial prostatitis and the characteristics of the models are summarized.
作者 王春雨 陈真
机构地区 中国药科大学药学医学基础实验教学中心
出处 《药学与临床研究》 2012年第1期60-63,共4页 Pharmaceutical and Clinical Research
关键词 慢性非细菌性前列腺炎 动物模型 炎症 Chronic nonbacterial prostatitis Animal model Inflammation
分类号 R965.1 [医药卫生—药理学]
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参考文献17

  • 1Krieger JN, Lee SW, Jeon J, et al. Epidemiology of prostatitis [J]. lnt J Antimicrob Agents, 2008, 31(suppl 1): S85-S90.
  • 2Radhakrishnan R, Nallu RS. Development and characterisation of a novel animal model of prostate inflam- mation-induced chronic pelvic pain [J]. Inflammopharmacology, 2009, 17(1): 23-8.
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  • 8张庆云,莫曾南,刘硒碲.姜黄素对慢性非细菌性前列腺炎大鼠TNF-α、IL-6和IL-8表达的影响[J].中华男科学杂志,2010,16(1):84-88. 被引量：19
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二级参考文献34

  • 1魏武然,张唯力,戴君勇.大鼠慢性非细菌性前列腺炎模型的建立[J].中国男科学杂志,2006,20(1):22-24. 被引量：67
  • 2潘萌,蒋浩琴,周芸,郑捷.弗氏佐剂与氢氧化铝佐剂对诱导小鼠获得性免疫应答作用的比较[J].现代免疫学,2006,26(2):98-101. 被引量：14
  • 3刘海红,夏欣一,黄宇烽.慢性前列腺炎与细胞因子研究进展[J].中华男科学杂志,2006,12(6):548-550. 被引量：22
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  • 5Wiygul RD, Prostatitis: Epidemiology of inflammation. Curt Urol Rep, 2005, 6(4) : 282-289.
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共引文献69

同被引文献161

引证文献12

二级引证文献42

药学与临床研究
2012年 第1期

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