血清同工铁蛋白水平在肝细胞癌切除术后的变化

VARIANCE OF SERUM ISOFERRITINS LEVEL AFTER RESECTION OF HEPATOCELLULAR CARCINOMA

本文报告血清同工铁蛋白在肝细胞癌切除术前后的变化情况。结果表明:血清酸性铁蛋白(SAF)水平在肝癌切除术后明显下降,其对照组,手术前后的SAF水平无变化。提示SAF是由肝癌组织合成分泌的,术后SAF水平测定可做为监测肝癌切除术后治疗效果的指标。血清铁蛋白(SF)水平在肝癌切除术后和肝脏其他手术后均升高,提示肝组织损伤是导致SF升高的原因之一,测定SF对肝癌切除术后疗效监测无意义。

This paper reported the variance of serum isoferritins level of17 patients with hepatocellular carcinoma (HCC) after resection. The level ofserum acid ferritin (SAF) decreased significantly after the resection ofHCC, but no such changes were found after operation in the control groups.These findings suggest that SAF is synthesized and secreted by the tissue ofHCC, and measuring the SAF level after the resection of HCC may be usedas an indicator for evaluating the effect of the resection of HCC. The serumferritin (SF) level was increased in both postresection of HCC and operationof other liver diseases. This result suggests that the damage of the livertissue is one of the factors which causes the increase of the SF level, andthe measurement of the SF level is not an efficient indicator for evaluatingthe result of surgical therapy.