广西肝癌高发区的散发性非甲非乙型肝炎

SPORADIC NON-A NON-B HEPATITIS IN GUANGXI HIGH LIVER CANCER INCIDENCE AREA

对来自广西肝癌高发区的204例散发急性病毒性肝炎患者研究的结果显示,非甲非乙型肝炎占47例(23％),乙型肝炎占92例(45％),甲型肝炎占63例(31％),巨细胞病毒感染占2例(1％),对2例所有乙肝病毒血清学指标均阴性的非甲非乙肝炎患者做了快速免疫电镜检查,结果在其中1例发现27nm病毒样颗粒。同时发现,有25％的急性非甲非肝炎转变成慢性。流行病学调查表明,在所有非甲非乙肝炎患者中,21.9％病前6个月内有经皮注射史,12.5％曾接触过病毒性黄疸肝炎病人,而65.6％找不到任何明确的感染途径。

204 sporadic patients with acute viral hepatitis living in Guangxihigh liver cancer incidence area were studied. The results showed that among204 cases, 23% had non-A non-B hepatitis (NANBH), 45% had hepatitis B,31% had heptitis A, and 1% had cytomegalic virus infection. Using rapidimmune electron microscopy, we saw 27 nm viruslike particles during theacute-phase sera in one of the two patients who had developed NANBHwithout any of the seromarkers of hepatitis B virus infection. It was foundthat 25% of all patients with NANBH became chronic. Epidemiologic surveysshowed that in all cases with NANBH, 21. 9% had a percutaneous injectionhistory, 12. 5% had contacted with icteric viral hepatitis patients, and 65. 6%couldn't be found attributable infective routes.