鼻咽黏膜下型癌临床及病理特点-附9例报告

Clinic-pathological characteristic of submucous nasopharynx carcinoma-nine cases reports

目的探讨鼻咽黏膜下型癌临床病理特点。方法回顾性分析9例临床确诊鼻咽黏膜下型癌患者临床资料。结果 9例患者中,6例患者颈部Ⅱ区淋巴结转移,3例颅底骨质破坏。平均每例活检次数1.1次,平均每例活检标本3.4块。病理分型:鳞状细胞癌中分化2例,低分化2例;未分化癌5例。镜下病理见鼻咽黏膜表层结构完整,癌组织呈孤立、灶状分布。结论鼻咽黏膜下型癌病理分化较差,侵袭性生长,癌变呈灶状分布,多位点、多层次活检有利于提高活检成功率。

[ Objective] To investigate the clinic-pathological characteristic of submucous nasopharynx carcinoma verified. [ Methods ] The records of nine patients with submucous nasopharynx carcinoma were retrospective viewed. [Results] Among nine cases, six cases had lymph node metastasis in level II, three cases basion involved. The av- erage biopsy times per case was 1.1, average samples 3.4 pieces. The pathologic differentiation included squamous cell carcinoma moderately was two cases, squamous cell carcinoma poorly two cases, and undifferentiation five cases. Pathological finding, the structure of surface of mucous was normal, focus of tumor was scattered as separation and piece. [Conclusion] Submucous nasopharynx carcinoma had poorly differentiation and strongly involved property, tumor loci appear isolated. Multi-site and biopsychosocial can enhance rate of diagnosis.