病毒相关血管炎

Viral infection-associated vasculitis

血管炎是指原发于血管壁及其周围组织的炎症变化，根据累及范围不同可分为系统性血管炎和皮肤血管炎。血管炎的病因复杂，研究表明，病毒感染是血管炎的致病原因之一，其中丙型肝炎病毒感染与原发性冷球蛋白血症、乙型肝炎病毒与结节性多动脉炎的相关性已被越来越多的研究证实，EB病毒、HIV病毒也可以诱发血管炎。有研究证明，很多皮肤血管炎与病毒感染有相关性。认识病毒感染与某些血管炎的相关性，有利于对血管炎发病机制的研究及指导临床血管炎的诊断和治疗。

Vasculitis refers to the inflammation of blood vessel walls and surrounding tissues. It can be divided into systemic vasculitis and cutaneous vasculitis according to the spectrum of involvement. The etiology of vaculitis is complex and viral infection is considered to be a cause of it. There has been increasing evidence for the association between hepatitis C virus and mixed cryoglobulinemia as well as between hepatitis B virus and polyarteritis nodosa. Epstein-barr virus and human immunodeficiency virus （HIV） can also induce vasculitis. Studies have confirmed the relationship between viral infection and cutaneous vasculitis. To recognize the relationship between viral infection and vasculitis is helpful for the diagnosis and therapy of vasculitis.