乙胺丁醇中毒性视神经病变的研究现状

Present status of ethambutol-induced optic neuropathy

乙胺丁醇是抗结核病治疗的一线用药,最主要的副作用之一是中毒性视神经病变.乙胺丁醇中毒性视神经病变的发生率、临床特征、危险因素、预后及发病机制等对其诊断和治疗有重要的现实意义.本文就这方面的研究现状作一综述.

Ethambutol is a commonly used first-line anti-tuberculosis agent,and its most important potential side-effect is ethambutol-induced optic neuropathy （EON）. Understanding of the incidence,clinical characteristics,risk factors,prognosis and mechanism of EON is of practical significance in the diagnosis and treatment of this disorder.This article reviews the present status of these aspects.