水溶性壳聚糖稀土配合物的合成、表征及其抑菌活性

Synthesis and Characterization of Chitosan-RE(Ⅲ) Complexes and Study on Antifungal Activity

[目的]研究水溶性壳聚糖及其稀土离子金属配合物的抑菌活性。[方法]合成水溶性壳聚糖和稀土离子La(Ⅲ)、Ce(Ⅲ)、Nd(Ⅲ)的配合物,利用FT-IR、UV-Vis和热重分析仪对配合物进行表征,研究壳聚糖及其配合物对芦笋茎枯病菌Phomopsis asparagus的抑制活性。[结果]壳聚糖Ce(Ⅲ)配合物对Phomopsis asparagus的抑菌活性较单一的水溶性壳聚糖及其他稀土配合物显著提高。[结论]水溶性壳聚糖稀土配合物抑菌活性分别为Ce(Ⅲ)配合物>La(Ⅲ)配合物>Nd(Ⅲ)配合物>壳聚糖。

[Aims] Antifungal activities of water-soluble complexes of chitosan-RE（III） were studied.[Methods] Water-soluble complexes of chitosan-La（Ⅲ）,Ce（III）,Nd（Ⅲ） were synthesized and characterized by FT-IR,UV-Vis spectra and TGA.The antifugal activities of chitosan and chitosan-RE（Ⅲ） complexes against Phomopsis asparagus were investigated.[Results] Chitosan-Ce（III） had the higher antifungal activity than water-soluble chitosan and other complexes.[Conclusions] The order of the antifungal activities of the complexes is Ce（Ⅲ）〉La（Ⅲ）〉Nd（Ⅲ）〉chitosan.