2010年咸阳市健康儿童乙型肝炎抗体水平监测结果

Monitoring results of hepatitis B antibody level among healthy children in Xianyang city in 2010

目的了解咸阳市健康儿童的乙型肝炎(乙肝)免疫水平,为今后如何有效开展基层乙肝疫苗接种提供科学依据。方法采用分层随机抽样和简单随机抽样的方法,抽取160名0～8岁儿童的血样,用酶联免疫吸附试验(ELISA)检测抗-HBs。结果该市0～8岁儿童抗-HBs阳性率为55.00%,年龄前组儿童(<3岁)抗-HBs阳性率(70.83%)高于学龄组(3～8岁)的阳性率(48.21%),3岁和8岁为2个抗-HBs阳性率高峰。结论应做好0～8岁儿童的乙肝疫苗查漏补种工作,提高儿童抗-HBs水平。

[Objective]To understand the immune level of hepatitis B among healthy children in Xianyang city,provide the scientific basis for exploring the feasible plan of hepatitis B vaccination.[Methods]With stratified random sampling and simple random sampling,the blood samples were collected from 160 children aged 0-8 years old,and anti-HBs level was detected by enzyme-linked immunosorbent assay（ELISA）.[Results]The positive rate of anti-HBs in 0-8 years old children was 55.00%.The positive rate（70.83%） of anti-HBs in low age group（under 3 years old） was higher than that（48.21%） of anti-HBs in high age group（3-8 years old）.The peaks of anti-HBs positive rate were 3 and 8 years old.[Conclusion]The missing detection and supplementary immunization should be implemented in children aged 0-8 years old,so as to improve the anti-HBs level among children.