甲状腺次全切除术对结节性甲状腺肿的临床疗效分析

The efficacy of subtotal thyroidectomy for nodular goiter

目的探究甲状腺次全切除术与甲状腺全切除术治疗结节性甲状腺肿的疗效。方法随机选取我院在2008年4月-2011年3月收治的需要手术治疗的甲状腺肿病人80例，将其随机分为试验组和对照细试验组行甲状腺次全切除术治疗，对照组行甲状腺全切除术治疗，比较两组患者围手术期相关指标、疗效以及并发症发病率。结果试验组其手术时间、术中出血量、镇痛药（曲马多）的使用量以及住院时间等均明显少于对照组（P〈0．05）。试验组并发症的发病率为5．0％，对照组的为22．5％，试验组并发症发病率明显低于对照组（P〈0．05）；两组患者有效率分别为95．0％、92．5％，有效率差异无显著性（P〉0．05）。结论对结节性甲状腺肿患者采用甲状腺次全切除术治疗，疗效确切，而且对患者损伤小，手术并发症少，值得在临床工作中开展应用。

Objective To explore the efficacy of subtotal thyroidectomy versus that of total thyroidectomy in the treatment of nodular goiter. Methods 80 patients who were hospitalized during the period of April 2008 to March 2011 and who needed surgical treatment were randomly divided into study group and control group. The study group received subtotal thyroidectomy whereas the control group received total thyroidectomy. The perioperation-related indices, the efficacy, and the complication rate were compared. Results The surgical duration and length of hospital stay were significantly shorter and intraoperative bleeding and dosage of analgesic use were smaller in the study group than in the control group （ P〈 0.05 ）. The complication rate was significantly lower in the study group than in the control group （ 5.0% vs. 22.5%, P 〈 0.05 ）. There was no statistically significant difference in the effectiveness rate between the two groups （ 95% vs. 92.5%, P 〉 0.05 ）. Conclusions Subtotal thyroidectomy is efficacious and less invasive and has less complications in the treatment of thyroid nodular goiter. It is worth applying in clinical practice.