翼状胬肉两种手术方法的治疗效果观察

Observation on therapeutic effects of two different surgical procedures for pterygium

目的探讨二种不同术式对翼状胬肉的治疗效果。方法翼状胬肉48例（54只眼）随机分成两组，A组23例（25只眼）翼状胬肉切除联合应用MMC；B组25例（29只眼、翼状胬肉切除加自体角膜缘干细胞移植。术后1周、2周、1个月、3个月、1年、2年检查记录术眼并发症及复发情况。结果随访观察6个月～2年，A组中有3只眼复发02％1，B组有2只眼复发（6．89％）。结论翼状胬肉切除加自体角膜缘干细胞移植能有效阻止胬肉复发，可重建和恢复角膜的眼表结构与功能，是目前较理想的手术方法，翼状胬肉切除联合应用MMC更适合年老体弱或不能耐受长时间手术患者。

Objective To evaluate the therapeutic effects of two different surgical procedures for pterygium. Methods A total of 48 patients （ 54 eyes） were randomly divided into two groups： 23 cases （ 25 eyes ） for group A using pterygium excision combined with mitomycin C and 25cases （29 eyes） for group B undergoing excision of pterygium with limbal epithelial autograft. The surgery complications and recurrence were observed by record inspection in 1 week, 2 weeks, 1 month, 3 months, 1 year and 2 years.Results All cases were followed up for 6 ~ 24 months. 3 eyes in group A was recurred （12%） while only 2 eyes in group B pterygium recurrence observed（ 6.89% ）.Conclusion Pterygium excision and clinical analysis of limbus epithelial stem cell autografting can prevent pterygium relapse, rebulid and recover the structure and function of cornea ocular surface. This is one ideal operation method up to now, pterygium excision combined with mitomycin C is more suitable for the elderly and frail people or for the patients who can not tolerate long time operation.